Tier 3:  Integrated Process Analytics

   Increasingly, NMR is becoming a step in a process.  Pharmaceutical companies demand spectra for more and more drug leads as information is generated earlier and earlier in the drug discovery process.  That means microfluidic sample management up front.  Protasis can tailor micro-unit-operations to your facility and ensure that samples are processed through the microNMR stage efficiently, rapidly and without loss of valuable sample.
 
By the way, you probably also want a mass spectrum from that valuable drug lead.  Fortunately, microNMR is non-destructive and well-matched for a follow-on electrospray-MS step.  Protasis can tailor downstream sample recovery, intermediate storage and transfer to additional analytical stages.  We can even provide custom microconsumables to serve your special research needs 

Key Benefits

  • Optimized analytics for your process
  • Full complement of microfluidic component technologies
  • Compact, cost-effective solutions using microfluidic manifolds

Capabilities

Structured System Design
Protasis can match fluid flows and sample concentrations between stages to optimize your hyphenated methods.  We can design and simulate mixers, reactors or separators based on fluid mechanics, reaction kinetics and heat or mass transfer principles.  Create an optimized sample management system for your high-throughput facility.
Multi-Disciplinary Competencies
In your physical world, Protasis can integrate filtration, concentration, separation and detection in one or multiple stages to manage your workflow.  In your virtual world, we can acquire and control your hyphenated instrument, database the chromatograms and spectra across your network and interpret and present the results. 
Custom Microconsumables
Protasis is finding that many capillary-scale techniques require tailored microconsumables to fit in with the procedures in today's high throughput drug discovery facility.  Protasis has created solid-phase-extraction and liquid chromatography cartridges that are optimized for automated sampling and analysis.
 

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