Protasis can confirm protein targets at high resolution using analytical Dynamic Field Gradient Focusing (DFGF) coupled to high-resolution electrospray mass spectrometry (e.g. Q-TOF). DFGF has sufficient resolution to isolate protein isoforms for complete characterization. Screening experiments may be facilitated by metering controlled amounts of target and leads using the Protasis low-dead volume mixer. Targets may be recovered from NMR screening experiments and reused.
Supported Operations
- Analytical Dynamic Field Gradient Focusing
- Sample Loading using HTSL
- Low Dead-Volume Mixing
Supported Studies
- Protein-Ligand Binding with NMR
